You would expect patients suffering from selective IgA deficiency to present with

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Study for the Success! In Clinical Laboratory Science – Immunology Test. Prepare with flashcards and multiple choice questions, each question offers hints and explanations. Get ready for your exam!

Multiple Choice

You would expect patients suffering from selective IgA deficiency to present with

Explanation:
Secretory IgA provides the first line of defense at mucosal surfaces, especially in the respiratory and gastrointestinal tracts. In selective IgA deficiency, the lack of this antibody weakens mucosal immunity, making infections at those sites more likely. That’s why recurrent respiratory tract infections are the classic presentation. Food allergies aren’t specifically driven by IgA levels, and septicemia implies a systemic infection rather than a mucosal one. Recurrent yeast infections aren’t the hallmark pattern for this deficiency, which centers on mucosal vulnerability rather than widespread or fungal-specific issues.

Secretory IgA provides the first line of defense at mucosal surfaces, especially in the respiratory and gastrointestinal tracts. In selective IgA deficiency, the lack of this antibody weakens mucosal immunity, making infections at those sites more likely. That’s why recurrent respiratory tract infections are the classic presentation.

Food allergies aren’t specifically driven by IgA levels, and septicemia implies a systemic infection rather than a mucosal one. Recurrent yeast infections aren’t the hallmark pattern for this deficiency, which centers on mucosal vulnerability rather than widespread or fungal-specific issues.

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