Which statement about B lymphocytes is correct?

Study for the Success! In Clinical Laboratory Science – Immunology Test. Prepare with flashcards and multiple choice questions, each question offers hints and explanations. Get ready for your exam!

Multiple Choice

Which statement about B lymphocytes is correct?

Explanation:
B lymphocytes are defined by having surface immunoglobulins that act as their antigen receptors. These membrane-bound antibodies recognize specific antigens, triggering activation, clonal expansion, and differentiation into plasma cells that secrete antibodies. They also present antigen to helper T cells via MHC II, supporting the adaptive response. Phagocytosis is a function of macrophages and neutrophils, not B cells. Antibody‑dependent cellular cytotoxicity is mainly carried out by natural killer cells and other Fc receptor–bearing effector cells, not by B cells themselves. The C5 component of the complement system is produced by the liver and other tissues, not by B lymphocytes. Thus, containing surface immunoglobulins is the best description of a key characteristic of B cells.

B lymphocytes are defined by having surface immunoglobulins that act as their antigen receptors. These membrane-bound antibodies recognize specific antigens, triggering activation, clonal expansion, and differentiation into plasma cells that secrete antibodies. They also present antigen to helper T cells via MHC II, supporting the adaptive response. Phagocytosis is a function of macrophages and neutrophils, not B cells. Antibody‑dependent cellular cytotoxicity is mainly carried out by natural killer cells and other Fc receptor–bearing effector cells, not by B cells themselves. The C5 component of the complement system is produced by the liver and other tissues, not by B lymphocytes. Thus, containing surface immunoglobulins is the best description of a key characteristic of B cells.

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