In an antibody titration that uses serial dilutions, how should the final antibody titer be reported?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Study for the Success! In Clinical Laboratory Science – Immunology Test. Prepare with flashcards and multiple choice questions, each question offers hints and explanations. Get ready for your exam!

Multiple Choice

In an antibody titration that uses serial dilutions, how should the final antibody titer be reported?

Explanation:
In this type of titration, you report the endpoint as the reciprocal of the highest serum dilution that still gives a positive reaction. That means you look for the last dilution that tests positive, and report that dilution’s reciprocal as the titer. If the serial dilutions remain positive up to 1:640 but become negative at 1:1280, the endpoint is 1:640, so the titer is 640 (the reciprocal of the last positive dilution). The other numbers would correspond to earlier, less-diluted endpoints and would only be reported if imaging the last positive dilution were smaller.

In this type of titration, you report the endpoint as the reciprocal of the highest serum dilution that still gives a positive reaction. That means you look for the last dilution that tests positive, and report that dilution’s reciprocal as the titer.

If the serial dilutions remain positive up to 1:640 but become negative at 1:1280, the endpoint is 1:640, so the titer is 640 (the reciprocal of the last positive dilution). The other numbers would correspond to earlier, less-diluted endpoints and would only be reported if imaging the last positive dilution were smaller.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy