Hashimoto disease is an autoimmune disorder primarily involving which gland?

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Study for the Success! In Clinical Laboratory Science – Immunology Test. Prepare with flashcards and multiple choice questions, each question offers hints and explanations. Get ready for your exam!

Multiple Choice

Hashimoto disease is an autoimmune disorder primarily involving which gland?

Explanation:
Hashimoto disease is an autoimmune attack focused on the thyroid gland. The immune system makes antibodies against thyroid components, such as thyroid peroxidase and thyroglobulin, and there is lymphocytic infiltration that gradually destroys thyroid follicles. This damages the gland’s ability to produce thyroid hormones, leading to hypothyroidism, and it can cause the thyroid to become enlarged (a goiter). Because the immune destruction centers on the thyroid, this gland is the primary site affected. The kidneys, liver, and lungs are not the typical targets in Hashimoto’s disease. This condition is defined by autoimmune thyroid involvement.

Hashimoto disease is an autoimmune attack focused on the thyroid gland. The immune system makes antibodies against thyroid components, such as thyroid peroxidase and thyroglobulin, and there is lymphocytic infiltration that gradually destroys thyroid follicles. This damages the gland’s ability to produce thyroid hormones, leading to hypothyroidism, and it can cause the thyroid to become enlarged (a goiter). Because the immune destruction centers on the thyroid, this gland is the primary site affected. The kidneys, liver, and lungs are not the typical targets in Hashimoto’s disease. This condition is defined by autoimmune thyroid involvement.

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