A molecule found in human serum sometimes used as a tumor marker is

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Study for the Success! In Clinical Laboratory Science – Immunology Test. Prepare with flashcards and multiple choice questions, each question offers hints and explanations. Get ready for your exam!

Multiple Choice

A molecule found in human serum sometimes used as a tumor marker is

Explanation:
Alpha-fetoprotein is a fetal protein produced by the liver and yolk sac, and in adults its levels are normally very low. When AFP is found at elevated levels in the serum, it serves as a tumor marker, most notably for hepatocellular carcinoma and certain germ cell tumors (such as yolk sac tumors). Clinically, AFP is used to help with diagnosis and, importantly, to monitor treatment response and detect recurrence. The other options aren’t tumor markers. HBsAg indicates active hepatitis B infection, not a tumor marker. Biotin is a vitamin that can interfere with some lab assays, but it is not a tumor marker. CD1 is an antigen-presenting molecule on immune cells, not something used to indicate cancer presence.

Alpha-fetoprotein is a fetal protein produced by the liver and yolk sac, and in adults its levels are normally very low. When AFP is found at elevated levels in the serum, it serves as a tumor marker, most notably for hepatocellular carcinoma and certain germ cell tumors (such as yolk sac tumors). Clinically, AFP is used to help with diagnosis and, importantly, to monitor treatment response and detect recurrence.

The other options aren’t tumor markers. HBsAg indicates active hepatitis B infection, not a tumor marker. Biotin is a vitamin that can interfere with some lab assays, but it is not a tumor marker. CD1 is an antigen-presenting molecule on immune cells, not something used to indicate cancer presence.

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